Telomerase相关论文
33. The Study of Mechanism By Which The Telomerase Template Phosphorothioate Antisense Oligonucleoti
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48. The value of CT scan and detection of telomerase activity in biopsy specimens for early diagnosi
Objective: To evaluate the diagnostic value of telomerase activity in the specimens of biopsy with bronchoscopy or cutti......
Most people associate the enzyme telomerase with its role in maintaining telomeres, which is its best-known canonical ro......
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[Pt(IQ)(DMSO)Cl](1)with 5,7-diiodo-8-hydroxyquinoline(H-IQ),were synthesized and fully characterized.1 is more selective......
Aim: The aim of the present study is to determine the role of adult hippocampal telomerase in the pathology of mood diso......
Telomerase reverse transcriptase gene from greasyback shrimp Metapenaeus ensis: isolation,genomic or
Telomerase plays a crucial role in the maintenance of telomere length and chromosome stability.It consists of a catalyti......
Changes of the telomerase activity and the expression for genes related with senescence during cellu
Objective To detect the alterations of the telomerase activity and the expression for genes response to oxidative stress......
Targeting EBV-LMP1 DNAzyme Enhances Radiosensitivity of Nasopharyngeal Carcinoma Cells by Inhibiting
The latent membrane protein 1 (LMP1),which is encoded by the Epstein-Barr virus (EBV) has been suggested to be one of th......
The jatrorrhizine was the major bioactive alkaloids isolated from Tinospora capillipes Gagnep.[1,2] It was important com......
A novel organoplatinum(Ⅱ)complex,[PtⅡ(QC1)(H-QC1)Cl](Pt1)bearing 3-(2′-quinolyl)-6,8-dichloro-coumarin(H-QC1)have bee......
Design,synthesis and interaction of 4,5-diazafluorene derivatives bearing 1,3-disubstituted pyrazole
Fifteen novel 4,5-diazafluorene derivatives bearing a 1,3-disubstituted pyrazol moiety were designed,synthesized,evaluat......
Design,synthesis and anticancer activity of 1,8-naphthalimide-uridine conjugates by targeting telome
G-quadruplex is formed in specific G-rich sequences such as telomere 3-overhang and the promoter of oncogenes....
Synthesis and DNA-binding studies of novel small molecules targeting human telomeric G-quadruplex DN
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Sensitive “off-on” electrochemiluminescence measuring assay for telomerase activity using self-enhan
Telomerase as a specialized reverse transcriptase in cells was used as tumor biomarker for the monitoring of cell carcin......
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Expression of telomerase activity, telomerase RNA component and telomerase catalytic subunit gene in
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Potent antitumoral effects of a novel gene-viral therapeutic system CNHK300-mEndostatin in hepatocel
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Aggregation-induced emission luminogens reveal cell cycle-dependent telomerase activity in cancer ce
Telomerase acts as an important biomarker for tumor identification, and synthesizes telomeric repeats at the end of chro......
Recent studies have demonstrated that many biological important processes are related to the conformation and assemb......
Stabilization of G-Quadruplex DNA,Inhibition of Telomerase Activity,and Tumor Cell Apoptosis by Coba
Two G-qudruplex ligands: [Co(H-La)2Cl2](Co1)and [Co(Lb)2][CoCl4]-2H2O(Co2)have been synthesized and characterized.Co......
Human Telomerase Reverse Transcriptase Activates the Expression of Vascular Endothelial Growth Facto
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会议
Trophoblast cells play vital roles in the processes of embryonic implantation and placentation.Many toxicological co......
With the many changes that have taken place in people’ s diet and lifestyle, colorectal cancer (CRC) has become a globa......
Gradient decrease in telomerase and its RNA in progressive passage of human endometrial stromal stem
The purpose of this study was to explore the change of telomerase in passage from human endometrial stromal stem cells i......
New NCI-N87-derived human gastric epithelial line after human telomerase catalytic subunit over-expr
AIM:To establish a cellular model correctly mimicking the gastric epithelium to overcome the limitation in the study of ......
目的研究放射联合中药单体对人宫颈癌（Me180）细胞增殖、端粒酶活性、细胞周期相关基因表达的作用。方法利用齐墩果酸、姜黄素和大蒜......
The changes in telomerase activity and telomere length in HeLa cells undergoing apop-tosis induced b
The changes in telomerase activity and telomere length during apoptosis in HeLa cells as induced by sodium butyrate (SB)......
Quantification of human telomerase RNA (hTR) and human telomerase reverse transcriptase (hTERT) mRNA
Aim: To evaluate the quantitative detection of human telomerase RNA (hTR) and human telomerase reverse tran-scriptase (......
MNS16A,a variable number of tandem repeats polymorphism in the TERT gene,has been suggested to regulate telomerase activ......
AIM:To follow the principles of evidence based medicine toreach the integrated results of these studies.METHODS:Twenty-......
目的 :研究端粒酶的 3种组分与其活性的关系 ,探讨端粒酶激活的关键因素。方法 :采用 TRAP法检测大肠癌组织及相邻正常黏膜组织中......
端粒与端粒酶的生物学研究已取得了一定进展 ,特别是证实端粒酶在肿瘤的发生发展上具有重要作用。根据报道统计[1～ 3] ,在恶性肿瘤......
Objective To investigate telomerase activity in chorion and decidua from abortion induced by mifepristone incorporated w......
该研究检测正常妊娠妇女和患先兆子痫妇女的胎盘中人端粒酶逆转录酶(human telomerase reverse transcriptase,hTERT)mRNA的水平,......
端粒对维护染色体功能的稳定起着不可替代的作用,端粒酶具有明显的抗氧化应激功能和保护线粒体的功能。端粒酶逆转录酶(hTERT)作为......
MNS16A,a variable number of tandem repeats polymorphism in the TERT gene,has been suggested to regulate telomerase activ......
